Description
Catalogue Number | IM004343 |
CAS No. | 385786-48-1 |
Chemical Name | Adaptaquin |
Synonyms | 7-[(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]-8-quinolinol |
Molecular Formula | C₂₁H₁₆ClN₃O₂ |
Molecular Weight | 377.82 |
Applications | General Uses:Ischemic injury Research, Renal anemia, HIF Prolyl Hydroxylase Inhibitor, Antioxidant, NeuroprotectiveDescription:Adaptaquin inhibits the HIF PHDs in brain in a dose dependent fashion and penetrates blood brain barrier (BBB). Exhibited functional recovery in intra-cerebral hemorrhage rat model; inhibits ATF4 gene. Potent HIF PHD inhibitor (hypoxia inducible factor), Selective PDH2 inhibitor.This compound is suitable for pyruvate dehydrogenase (PDH) related research. |
Category | Research Tools; Standards; Molecular Biology; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.
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