Des(N-Methyl-leucyl), N-tertButyloxycarbonyl-leucyl Cyclosporin A seco(MeGly-MeLeu) Methyl Ester
- Catalogue No.: IM024816
- CAS No.: —
- Mol. Formula: C₆₉H₁₂₃N₁₁O₁₆
Description
| Catalogue Number | IM024816 |
| CAS No. | — |
| Chemical Name | Des(N-Methyl-leucyl), N-tertButyloxycarbonyl-leucyl Cyclosporin A seco(MeGly-MeLeu) Methyl Ester |
| Synonyms | N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester |
| Molecular Formula | C₆₉H₁₂₃N₁₁O₁₆ |
| Molecular Weight | 1362.78 |
| Appearance | White Solid |
| Solubility | Acetone, DCM, Methanol |
| Applications | N-Boc-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester is an intermediate in the synthesis of Cyclosporin AM 4N (C989410), a metabolite of Cyclosporin A (C988900). Cyclosporin A is a hydrophobic cyclic undecapeptide that is used as a potent immunosuppressive agent that has application in human organ transplantation. Cyclosporin A works by inhibiting subsets of T lymphocytes to facilitate organ transplantation. |
| Category | Research Tools; Molecular Biology; Amino Acids/Peptides; |
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