2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate

  • Catalogue No.: IM080498
  • CAS No.: 351330-42-2
  • Mol. Formula: C₂₄H₁₉NO₈S₂

Description

Catalogue Number IM080498
CAS No. 351330-42-2
Chemical Name 2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate
Synonyms Methanesulfonothioic Acid S-[3-[(3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]-3-oxopropyl] Ester; MTS-4-Fluorescein
Molecular Formula C₂₄H₁₉NO₈S₂
Molecular Weight 513.54
Appearance Yellow to Pale Orange to Red Solid
Melting Point >162°C dec.
Storage -20°C, Inert atmosphere
Solubility DMSO (Slightly), Methanol (Slightly)
Applications A thiol specific fluorescent probe useful for ion channel and protein topology research. The recently available MTS-fluorophores may find application in the real-time monitoring of conformational changes, since fluorophores coupled to introduced cysteines can change their fluorescence during a conformational change. Fluorescence lifetime may also yield information regarding distances and molecular motion in a protein molecule.Fluorescence: max. Abs. 492nm; max. Em. 515nm; e x 10-3: 75
Category Standards; Fluorescent Reagents; Sulfhydryl Active Reagents;

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