Des(N-Methyl-leucyl), Leucyl Cyclosporin A seco(MeGly-MeLeu) Carboxylic Acid

  • Catalogue No.: IM101974
  • CAS No.:
  • Mol. Formula: C₆₃H₁₁₃N₁₁O₁₄

Description

Catalogue Number IM101974
CAS No.
Chemical Name Des(N-Methyl-leucyl), Leucyl Cyclosporin A seco(MeGly-MeLeu) Carboxylic Acid
Molecular Formula C₆₃H₁₁₃N₁₁O₁₄
Molecular Weight 1248.64
Appearance White Solid
Solubility Methanol
Applications L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine is an intermediate in the synthesis of Cyclosporin AM 4N (C989410), a metabolite of Cyclosporin A (C988900). Cyclosporin A is a hydrophobic cyclic undecapeptide that is used as a potent immunosuppressive agent that has application in human organ transplantation. Cyclosporin A works by inhibiting subsets of T lymphocytes to facilitate organ transplantation.
Category Research Tools; Molecular Biology; Amino Acids/Peptides;

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