3-O-Methyl-L-DOPA-d3 Monohydrate

  • Catalogue No.: IM109792
  • CAS No.: —
  • Mol. Formula: C₁₀H₁₀D₃NO₄ • H ₂O
SKU: IM109792 Categories: , , , ,

Description

Catalogue Number IM109792
CAS No. —
Alternate CAS No. not a hydrate: 586954-09-8200630-46-2 -unlabelled
Chemical Name 3-O-Methyl-L-DOPA-d3 Monohydrate
Synonyms 3-(Methoxy-d3)-L-tyrosine Monohydrate; 3-(Methoxy-d3)-4-hydroxyphenylalanine Monohydrate; 3-(Methoxy-d3)-DOPA Monohydrate; 3-(Methoxy-d3)-L-tyrosine Monohydrate; 3-O-(Methyl-d3)dopa Monohydrate; L-3-(Methoxy-d3)-4-hydroxy-
Molecular Formula C₁₀H₁₀D₃NO₄ • H ₂O
Molecular Weight 214.24 + 18.02
Appearance White to Off-White Solid
Melting Point 223-228°C
Storage 4°C, Hygroscopic
Solubility Aqueous Acid (Slightly), DMSO (Slightly)
Stability Hygroscopic
Applications Labelled 3-O-Methyl-L-DOPA (M303815). 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-Methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA.
Category Standards; Amino Acids; Isotopic Labeled Analogues; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;

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