Des(N-Methyl-leucyl) Cyclosporin A seco(MeGly-MeLeu) Methyl Ester

  • Catalogue No.: IM146960
  • CAS No.: 156047-45-9
  • Mol. Formula: C₅₈H₁₀₄N₁₀O₁₃

Description

Catalogue Number IM146960
CAS No. 156047-45-9
Chemical Name Des(N-Methyl-leucyl) Cyclosporin A seco(MeGly-MeLeu) Methyl Ester
Molecular Formula C₅₈H₁₀₄N₁₀O₁₃
Molecular Weight 1149.51
Appearance Yellow Solid
Solubility Acetone, DCM, Methanol
Applications L-Valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester is an intermediate in the synthesis of Cyclosporin AM 4N (C989410), a metabolite of Cyclosporin A (C988900). Cyclosporin A is a hydrophobic cyclic undecapeptide that is used as a potent immunosuppressive agent that has application in human organ transplantation. Cyclosporin A works by inhibiting subsets of T lymphocytes to facilitate organ transplantation.
Category Standards; Chiral Molecules; Amino Acids/Peptides; Pharmaceutical/API Drug Impurities/Metabolites;

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