설명
Catalogue Number | IM003067 |
CAS No. | — |
Chemical Name | (Z)-7-((S)-2-Azido-2-carboxyethyl)thio Cilastatin Derivative |
Synonyms | (Z)-7-(((S)-2-Azido-2-carboxyethyl)thio)-2-((R)-2,2-dimethylcyclopropane-1-carboxamido)hept-2-enoic Acid; |
Molecular Formula | C₁₆H₂₄N₄O₅S |
Molecular Weight | 384.45 |
Appearance | Yellow syrup |
Storage | -20°C |
Solubility | Dichloromethane |
Applications | (Z)-7-((S)-2-Azido-2-carboxyethyl)thio Cilastatin Derivative is an intermediate in the synthesis of (Z)-7-(((2R)-2-Carboxy-2-((4-oxopentan-2-yl)amino)ethyl)thio)-2-((S)-2,2-dimethylcyclopropanecarboxamido)hept-2-enoic Acid (C178930), an impurity of Cilastatin (C441100), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct. |
Category | Building Blocks; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.
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