설명
Catalogue Number | IM005127 |
CAS No. | 2482-00-0 |
Alternate CAS No. | Free Base: 306-60-5 |
Chemical Name | Agmatine Sulfate |
Synonyms | N-(4-aminobutyl)guanidine Sulfate; NIH 11035 |
Molecular Formula | C₅H₁₆N₄O₄S |
Molecular Weight | 228.27 |
Appearance | White to Off-White Solid |
Melting Point | 231-233°C |
Storage | 20°C |
Solubility | Water (Slightly, Heated) |
Applications | General Uses: Neuroprotective, CNS studies, Autism and depression researchDescription:Agmatine Sulfate is a polyamine derived from L-arginine (A769500) decarboxylation and is a known putative endogenous neurotransmitter at imidazoline receptors. Agmatine sulfate displaces clonidine at a2-adrenergic and at imidazoline receptors and was recently shown to exert some neuroprotective effects. It blocks NMDA-receptor associated cation channels. Acts as a competitive inhibitor of nitric oxide synthase (NOS). It functions as neurotransmitter since it is stored in synaptic vesicles and is related from axon terminals by depolarization(1). Protects autistic behavior in rats (2) and reverses depressive like behavior in mice. (3) |
Category | Standards; Amino Acids; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.
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