Description
Catalogue Number | IM100163 |
CAS No. | 487-79-6 |
Chemical Name | (-)-α-Kainic Acid |
Synonyms | (2S,3S,4S)-2-Carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic Acid; 2-Carboxy-4-isopropenyl-3-pyrrolidineacetic Acid; (-)-Kainic Acid; (2S,3S,4S)-2-Carboxy-4-isopropenylpyrrolidine-3-acetic Acid; Digenic Acid; Digenin; Helminal; Kainic Acid; L-α-Kainic Acid; α-Kainic Acid |
Molecular Formula | C10H15NO4 |
Molecular Weight | 213.23 |
Appearance | White to Off-White Solid |
Melting Point | >208°C (dec.) |
Storage | Hygroscopic, -20°C Freezer, Under inert atmosphere |
Solubility | Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly) |
Applications | (-)-α-Kainic Acid is a naturally occurring neuroexcitatory chemical that is an selective agonist for a subtype of ionotropic glutamate receptor. Administration of (-)-α-Kainic Acid has been shown to increase production of reactive oxygen species, mitochondrial dysfunction, and apoptosis in neurons in many regions of the brain, particularly in the hippocampal subregions and in the hilus of dentate gyrus. |
Category | Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.