6-Hydroxy-L-DOPA
- Catalogue No.: IM092337
- CAS No.: 27244-64-0
- Mol. Formula: C₉H₁₁NO₅
Description
| Catalogue Number | IM092337 |
| CAS No. | 27244-64-0 |
| Chemical Name | 6-Hydroxy-L-DOPA |
| Synonyms | 2,4,5-Trihydroxy-L-phenylalanine; 2,4,5-Trihydroxyphenylalanine; 2,5-Dihydroxy-L-tyrosine; 3-(3,4,6-Trihydroxyphenyl)-L-alanine; 6-Hydroxy-L-DOPA; Hydroxy-L-dopa; L-6-Hydroxydopa; TOPA; Levodopa EP Impurity A; Levodopa USP Related Compound A |
| Molecular Formula | C₉H₁₁NO₅ |
| Molecular Weight | 213.19 |
| Appearance | Brown to Black Solid |
| Melting Point | >190°C (dec.) |
| Storage | -20°C, Hygroscopic |
| Solubility | Aqueous Acid (Slightly, Sonicated), Water (Slightly, Heated, Sonicated) |
| Stability | Air Sensitive, Hygroscopic |
| Applications | 6-Hydroxy-L-DOPA (Levodopa EP Impurity A; Levodopa USP Related Compound A) is the 6-hydroxy derivative of the amino acid L-DOPA (D533751) with neurotoxic properties. Studies show that exogenously administered 6-Hydroxy-L-DOPA is biotransformed by amino acid decarboxylase to the highly potent and catecholamine-selective neurotoxin, 6-Hydroxydopamine. The treatment of 6-Hydroxy-L-DOPA in rats resulted in the stimulation of acetylcholinesterase. |
| Category | Standards; Amino Acids; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.
