AF 12198
- Catalogue No.: IM004853
- CAS No.: 185413-30-3
- Mol. Formula: C₉₆H₁₂₃N₁₉O₂₂
Description
| Catalogue Number | IM004853 |
| CAS No. | 185413-30-3 |
| Chemical Name | AF 12198 |
| Molecular Formula | C₉₆H₁₂₃N₁₉O₂₂ |
| Molecular Weight | 1895.12 |
| Appearance | White to Off-White Solid |
| Melting Point | >179°C (dec.) |
| Storage | 4°C |
| Solubility | DMSO (Slightly), Methanol (Slightly), Water (Very Slightly) |
| Applications | N-Acetyl-L-phenylalanyl-L-a-glutamyl-L-tryptophyl-L-threonyl-L-prolylglycyl-L-tryptophyl-L-tyrosyl-L-glutaminyl-(2S)-2-azetidinecarbonyl-L-tyrosyl-L-alanyl-L-leucyl-L-prolyl-L-Leucinamide is a peptide that selectively binds Interleukin-1 (IL-1) receptor and blocks in vivo responses to IL-1 (1). The interleukin-1 receptor can activate the innate immune response by binding to cytokines (2). Dysregulation of cytokine production can lead to aberrant immune cells activation that could result in auto-inflammatory disorders. |
| Category | Standards; Amino Acids/Peptides; |
Note: All Products are stable to be shipped at room temperature, unless otherwise specified.
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