CP-154526 Hydrochloride

  • Catalogue No.: IM047252
  • CAS No.: 257639-98-8
  • Mol. Formula: C23H33ClN4

Description

Catalogue Number IM047252
CAS No. 257639-98-8
Alternate CAS No. 157286-86-7
Chemical Name CP-154526 Hydrochloride
Synonyms N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Hydrochloride ; CP 154526 Hydrochloride ;
Molecular Formula C23H33ClN4
Molecular Weight 400.99
Appearance Pale Yellow Solid
Melting Point 167-169°C
Storage Refrigerator
Solubility DMSO, Methanol
Applications CP-154526 Hydrochloride is a selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1) (1,2,3). It blocks CRF-induced adenylate cyclase activation and attenuates activation of the HPA axis by CRF and displays anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant.
Category Standards; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;

Note: All Products are stable to be shipped at room temperature, unless otherwise specified.