Cyclosporin A seco(MeGly-MeLeu) Methyl Ester
- Catalogue No.: IM110979
- CAS No.: 286852-20-8
- Mol. Formula: C₆₅H₁₁₇N₁₁O₁₄
Description
| Catalogue Number | IM110979 |
| CAS No. | 286852-20-8 |
| Chemical Name | Cyclosporin A seco(MeGly-MeLeu) Methyl Ester |
| Synonyms | Cyclosporin A open ring |
| Molecular Formula | C₆₅H₁₁₇N₁₁O₁₄ |
| Molecular Weight | 1276.69 |
| Appearance | Off-White Solid |
| Solubility | DCM, Methanol |
| Applications | N-Methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-glycine Methyl Ester is an intermediate in the synthesis of Cyclosporin AM 4N (C989410), a metabolite of Cyclosporin A (C988900). Cyclosporin A is a hydrophobic cyclic undecapeptide that is used as a potent immunosuppressive agent that has application in human organ transplantation. Cyclosporin A works by inhibiting subsets of T lymphocytes to facilitate organ transplantation. |
| Category | Research Tools; Molecular Biology; Amino Acids/Peptides; |
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