Memantine

Catalogue No.: IM104420
CAS No.: 19982-08-2
Mol. Formula: C₁₂H₂₁N

Description

Catalogue Number	IM104420
CAS No.	19982-08-2
Chemical Name	Memantine
Synonyms	3,5-Dimethyltricyclo[3.3.1.13,7]decan-1-amine; 1,3-Dimethyl-5-adamantanamine; 1,3-Dimethyl-5-aminoadamantane; 1-Amino-3,5-dimethyladamantane
Molecular Formula	C₁₂H₂₁N
Molecular Weight	179.3
Appearance	Colorless Oil to Off-White Waxy Solid
Melting Point	No data available
Storage	4°C, Inert atmosphere
Solubility	Chloroform (Slightly), DMSO (Slightly)
Applications	Recent phase 3 clinical trials have shown that Memantine is an effective way of treatment of both mild and moderate-to-severe Alzheimer's disease and possibly vascular dementia (multi-infarct dementia). MemantineтАЩs method of action involves an uncompetitive, low-affinity, open-channel blocker; it enters the receptor-associated ion channel preferentially when it is excessively open, and, most importantly, its off-rate is relatively fast so that it does not substantially accumulate in the channel to interfere with normal synaptic transmission.
Category	Standards; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;

Note: All Products are stable to be shipped at room temperature, unless otherwise specified.